Problems that occur in addition to the desired therapeutic effect. Allgulander et al. (2004) list the following in their study: Asthenia, Anorexia, Constipation, Dry mouth, Nausea, Anxiety, Dizziness, Insomnia, Libido decreased, Somnolence, Tremor, Sweating, Abnormal ejaculation, Anorgasmia, Impotence.

Some reports online group many systems into two clusters: symptoms of being tired vs. those of feeling wired. Tired in this context would include fatigue, lethargy, and low energy. But these would not be like apathy due to the sadness of depression, but more like too mellow, the opposite of feeling wired. Symptoms of being wired would include feeling agitated, tense, edgy, irritable, as well as possible insomina and even hypertension. This feeling would be more like being hyper after too much coffee, rather than the emotional anxiety typical of GAD.

Fatigue. A condition characterized by a lessened capacity for work and reduced efficiency of accomplishment, usually accompanied by a feeling of weariness and tiredness. Fatigue can be acute and come on suddenly or chronic and persist.

Insomnia. The perception or complaint of inadequate or poor-quality sleep because of one or more of the following: difficulty falling asleep; waking up frequently during the night with difficulty returning to sleep; waking up too early in the morning; or unrefreshing sleep. Insomnia is not defined by the number of hours of sleep a person gets or how long it takes to fall asleep. Individuals vary normally in their need for, and their satisfaction with, sleep. Insomnia may cause problems during the day, such as tiredness, a lack of energy, difficulty concentrating, and irritability.